Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0003p038 | (1) | SRF2016

The impact of the selective progesterone receptor modulator (SPRM), ulipristal acetate (UPA) administration upon cell proliferation markers within the human endometrium

Matthews Rebecca , Murray Alison , Whitaker Lucy , Millar Michael , Nicol Moira , Williams Alistair , Critchley Hilary

Introduction: Selective progesterone receptor modulators (SPRMs) have been reported to decrease cell proliferation within uterine fibroids, and reduce menstrual blood loss. The SPRM Ulipristal Acetate (UPA) has an anti-proliferative effect on fibroid tissue, yet its impact on endometrial cell proliferation is not well understood. The aim of this study was to quantify the effects of the SPRM UPA administration on endometrial cell proliferation within the human endometrium.<...